The invention provides a negative-pressure oxygen-carrying wound treatment device, and belongs to the field of medical apparatus. The wound treatment device disclosed by the invention is provided with a control module, as well as oxygen production equipment and an oxygen delivery pipe which are sequentially connected, and negative-pressure equipment, a negative-pressure tube, a liquid collection bottle and a drainage tube which are sequentially connected. An oxygen production control end is arranged on the control module for controlling the oxygen production equipment and a negative-pressure control end is arranged on the control module for controlling the negative-pressure equipment; and an oxygen bottle, which is provided with an oxygen concentration sensor, is arranged for regulating and controlling an oxygen concentration supplied to a wound and an air pressure sensor is arranged for regulating and controlling a negative-pressure vacuum degree supplied to the wound. The wound treatment device disclosed by the invention has a function of alternately supplying negative pressure and oxygen to the wound, so that a clinical working efficiency is improved and the disease recovery of a patient is promoted; and the wound treatment device has the characteristics of simple structure, good using effect and broad application scope to occasions.