The invention discloses a novel heat preservation box for apparatus and instrument. The novel heat preservation box comprises a heat preservation box body, an apparatus and instrument measuring wire outlet, a power wire inlet, a heater and a temperature controller; the heat preservation box body comprises a metal casing layer, a wood material layer and a heat preservation cotton layer which are arranged from outside to inside successively; the apparatus and instrument measuring wire outlet and the power wire inlet are arranged in the lateral side of the heat preservation box body; the heater is arranged in the bottom and two sides of the heat preservation box body; the temperature controller is used to control the state of the heater so that the temperature in the heat preservation box body is constant; and the inner side of the power wire inlet is provided with a rubber heat insulating curtain. The heat preservation box for apparatus and instrument has the advantages of being simple in structure, low in consumption power, convenient to use, portable and movable, is not influenced by too low temperature in window, is especially suitable for alpine regions, and can improve the working reliability and maintenance efficiency of the instrument and apparatus.