The invention provides an anti-oxidation material and a preparation method thereof. The anti-oxidation material can be used as a nonstick pan coating layer. The preparation method of the anti-oxidation material comprises the following steps: 1, dissolving astaxanthin in dimethyl formamide, adding poly(aryl ether nitrile ketone) to the above obtained solution, uniformly mixing poly(aryl ether nitrile ketone) and the obtained solution, reacting poly(aryl ether nitrile ketone) with the solution at 50-80DEG C for 60-120min to obtain a first reaction product; 2, adding a silane coupling agent to the first reaction product, and reacting the silane coupling agent with the first reaction product at 50-80DEG C for 60-120min to obtain a second reaction product; 3, fully and uniformly mixing methyltriethoxysilane, methyl tert-butyl ether, azodicarbonamide, diphenyldimethoxysilane and deionized water, adding the second reaction product to the obtained mixed solution, reacting the second reaction product with the mixed solution at a constant temperature of 30-50DEG C for 3-5h, carrying out normal pressure distillation at 60-90DEG C to evaporate most of solvents, reducing the pressure to -0.08MPa, slowly heating the above system to 120-160DEG C, and keeping the temperature for 30-60min to obtain a third reaction product; and 4, placing the third reaction product in a mixer, and carrying out extruding granulation to obtain the anti-oxidation material.