The invention provides a quality detection method of hericium erinaceus tablets. The method comprises steps as follows: (1) preparation of a mixed standard solution, (2) preparation of a test solution, (3) creating of chromatographic conditions, (4) drawing of a standard curve and regression calculation, (5) measurement of the test solution. The invention further provides the hericium erinaceus tablets obtained through detection with the quality detection method. By means of the quality detection method, the quality of the hericium erinaceus tablets can be comprehensively monitored, the stability of a production process is monitored, the stability, the uniformity and the controllability of a product are guaranteed, the method can also be used for identifying a counterfeit product, and accordingly, normal production and the circulation sequence of the variety of medicines are guaranteed.