Embodiments of the invention disclose an application program unloading method. The method comprises the following steps: receiving an unloading operation instruction aiming at a target application program; calling a pre-configured first processing function for unloading application programs according to the unloading operation instruction; when judging that an equipment manager option switch which is correspondingly opened by the target application program needs to be closed through running the first processing function, triggering and calling a pre-configured second processing function for closing the equipment manager option switch; and when closing the equipment manager option switch through running the second processing function, unloading the target application program through the first processing function. The invention furthermore discloses an application program unloading device. By adopting the application program unloading method and device, the technical problem that the conventional unloading manner in the prior art cannot unload application programs can be solved, the security of mobile electronic equipment is improved, the rapid and convenient unloading of the application programs can be realized, and the requirement for easily and intelligently the application programs by the users can be satisfied.