The invention provides a traditional Chinese medicine composition capable of resisting fatigue and enhancing immunity. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15 parts of Chinese chive seed extract, 5 parts of antler powder, 20 parts of poria cocos, 30 parts of radix astragali seu hedysari and 30 parts of rhizoma dioscoreae. Compared with the prior art, the traditional Chinese medicine composition provided by the invention has the advantages of safety, effectiveness, high cost performance and the like, and is capable of helping people resist the fatigue, enhance the immunity and the like.