The invention relates to an adjustable gypsum plate cutter. The adjustable gypsum plate cutter comprises a main frame, a cutting module, an adjusting rod, a fixed cross bar and a handle; the adjusting rod and the fixed cross bar are arranged on the main frame; the handle is arranged on the fixed cross bar; the cutting module is arranged on the adjusting rod, and can move along the adjusting rod; and a blade is arranged on the cutting module. The adjustable gypsum plate cutter realizes size-adjustable quick cutting through adjusting the angle, the distance and the number of the cutting module, largely reduces the dust pollution effect and the harm to environments and human bodies through simulating a cutting mode of an artificial art knife, and isolates bodies of operators from the blade through the handle to preferably protect the body safety of the operators.