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Invention Grant
CN105969868B MAP7在CN-AML组织样品中表达水平的检测方法及其应用 失效 - 权利终止

MAP7在CN-AML组织样品中表达水平的检测方法及其应用
Abstract:
MAP7在CN‑AML组织样品中表达水平的检测方法及其应用。本发明提供了微管结合蛋白7基因的引物对，其中之一引物对的序列是tcctgggagctgcaattaca(SEQ ID NO：2)和gggtgcttttggtcttctgg(SEQ ID NO：3)或者它们的互补序列。本发明引物对用于通过检测微管结合蛋白7的表达高低而对正常核型急性髓系白血病患者危险度分层或预后评估。本发明还提供了包含所述引物对的基因芯片和试剂盒。
Abstract(English):

The invention discloses a method for detecting the expression level of MAP7 in a CN-AML tissue sample and an application thereof. The invention provides primer pairs of a microtubule-associated protein 7 gene, wherein the sequences of one primer pair are tcctgggagctgcaattaca (SEQ ID NO:2) and gggtgcttttggtcttctgg (SEQ ID NO:3) or complementary sequences thereof. In the invention, the primer pairs are used for performing risk stratification or clinical prognosis evaluation for patients suffering normal karyotype acute myelogenous leukemia by detecting the expression level of microtubule-associated protein 7. The invention also provides a gene chip and a kit comprising the primer pairs.

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