The invention belongs to the pressure sensing technology and provides a pressure transducer circuit and a commissioning method thereof. The pressure transducer circuit comprises four parts including a circuit voltage reference circuit (1), a sensitive electrical bridge (2), a voltage amplifier circuit (3) and a current conversion circuit (4). The pressure transducer circuit, by reasonably selecting voltage reference, operational amplifier and other mainly devices, reduces supply voltage of a Wheatstone pressure sensitive electrical bridge and increases the resistance of a zero voltage dividing adjusting resistor, so that the static consumption current of the transducer signal conditioning circuit is no greater than 3.8mA, and the commissioning requirement of the pressure transducer is satisfied. High magnification of weak signals of a pressure sensitive electrical bridge is realized through reasonably determining the amplification times of a three op-amp instrumentation amplification circuit and the capacity of parallel porcelain capacitors on a negative feedback resistor of a voltage amplifier circuit, and the circuit is provided with excellent stability.