The invention discloses a synchronous rectification control driver. The synchronous rectification control driver in the prior art is large in size and high in cost and loss, and particularly, the values of resistors are difficult to consider under the situation that the rectification current is greatly different. The synchronous rectification control driver comprises a first diode D1, a second diode D2, a third diode D3, a first resistor R1, a second resistor R2, a third resistor R3, a fourth resistor R0, a fifth resistor Rg, a comparator U, a first synchronous rectifier tube Q1, a second synchronous rectifier tube Q2 and a synchronous rectifier MOSFET (Metal Oxide Semiconductor Field Effect Transistor). The synchronous rectification control driver realizes reliable blocking of reverse voltage during turn-off of synchronous rectifier tubes, and simultaneously realizes an integrated structure of sampling, closed-loop control and driving of high-speed and precision detection of synchronous rectifier tube current directions.