The invention discloses an infusion pump cassette and a cassette interface configured to assist cassette removal. A cassette apparatus for an infusion pump includes a cassette for operatively connecting administration set tubing to the infusion pump and a cassette interface a cassette interface on the infusion pump for removably receiving the cassette. The cassette includes a press tab having an upwardly facing press surface and an undersurface, and the cassette interface includes at least one fulcrum member, wherein the undersurface of the press tab engages the fulcrum member(s) when the cassette is received by the cassette interface. As a result, the cassette is pivotable relative to fulcrum member(s) by pressing the press surface of the press tab to assist in removing the cassette from the cassette interface.