The invention discloses a screw separating and conveying mechanism with five blocking parts and six clamping parts. The screw separating and conveying mechanism comprises a machine frame, a separating mechanism and an air blocking mechanism; the separating mechanism comprises six openable outputting clamping blocks, the outputting clamping blocks can respectively form a chuck type clamping opening fixing a single screw, the chuck type clamping openings are aligned to a screw track and are connected to the screw track, a gap allowing the single screw to pass through is formed, and when the outputting clamping blocks rotate to the open state, screws are output through an outputting port formed below the outputting clamping blocks; the air blocking mechanism is arranged on the outputting port and comprises air blocking blades. According to the screw separating and conveying mechanism, the single screw is selected and output through rotating, opening and closing of the outputting clamping blocks, and therefore the failure rate can be effectively lowered; the air blocking mechanism is adopted for closing and opening the outputting port reasonably, and therefore blowing at the lower part does not influence separating at the upper part. The screw separating and conveying mechanism with the five blocking parts and the six clamping parts has the beneficial effects that the separating effect is good and the failure rate is low.