The invention relates to a graphene-based antistatic wear-resistant two-component epoxy resin coating. The coating is prepared from a component A and a component B; the component A and the component B are at the weight ratio of (2-5):1; the component A comprises 100 weight parts of mixed epoxy resin, 3 to 5 weight parts of graphene, 3 to 10 weight parts of an antioxidant, 30 to 50 weight parts of filler, 2 to 5 weight parts of a dispersing agent and 1 to 3 weight parts of a pigment; the component B comprises 20 to 30 weight parts of hydroxyl-terminated polyurethane oligomer, 5 to 10 weight parts of graphene oxide, and 15 to 25 weight parts of a multifunctional epoxy curing agent. The cured product of the coating has excellent antistatic property, wear resistance and thermal conductivity; the comprehensive performance is excellent and is superior to similar products in the prior art.