The invention discloses a 110Ksi steel grade hydrogen sulfide stress corrosion-resistant steel pipe for an oil well and a production method thereof. The steel pipe comprises the following components by mass percent: 0.20 to 0.28% of C, 0.12 to 0.35% of Si, 0.4 to 0.8% of Mn, 0.001 to 0.011% of P, 0.0001 to 0.003% of S, 0.9 to 1.4% of Cr, 0.7 to 1.2% of Mo, 0.0003 to 0.003% of B, 0.02 to 0.045% of Nb, 0.04 to 0.08% of V, 0.005 to 0.05% of Al, 0 to 0.1% of Zr, 0 to 0.3% of Ni, 0 to 0.15% of Cu, 0 to 0.01% of La, 0 to 0.002% of O, 0 to 0.009% of N and 0 to 0.00015% of H, and the balance being Fe and unavoidable impurities. The production method of the steel pipe sequentially comprises the steps of electric furnace smelting, external refining, vacuum degassing, continuous casting and rolling, steel billet heating, steel pipe rolling, and quenching and tempering and straightening. The steel pipe has excellent physical and chemical properties, the index meets the API requirement, the hydrogen sulfide stress corrosion resistance threshold value reaches 90%YS min, the average grain size is 10 grade and is higher than the API requirement, and the steel pipe is applicable to an oil and gas field with a hydrogen sulfide environment, and is safe and efficient.