The invention provides a method for collaborative governance of gas and coal spontaneous combustion of a fully-mechanized caving face with a single thick coal seam. The method is suitable for collaborative governance of gas and coal spontaneous combustion disasters of the fully-mechanized caving face with the spontaneous tendency, the single thick coal seam and large gas emission. Macromolecular air leaking stoppage materials are sprayed to air inlet and return gate roadways of the caving face to form an air leaking stoppage system. In the recovery process, high-order drill holes and grouting holes are alternately formed in the air return gate roadway side, and the high-order drill holes and the grouting holes are kept reasonably spaced to form a gas drainage and grouting system. Monitoring and prewarning systems are established at relevant positions of the caving face, the safety state of the caving face is monitored at any time, and all the systems collaboratively work to achieve the purpose of collaborative governance of the gas and coal spontaneous combustion disasters of the fully-mechanized caving face with the single thick coal seam. The method for collaborative governance of gas and coal spontaneous combustion of the fully-mechanized caving face with the single thick coal seam is scientific, effective, simple and easy to carry out, does not delay production, and can guarantee rapid and efficient exploitation of the caving face.