The invention discloses an intelligent printing system with a data dynamic interactive function and a method with the data dynamic interactive function, which relates to the field of data processing. The printing system comprises a data processing server, a printing device and an upper computer. The data processing server is in bidirectional data communication with the printing device. The printing device is in bidirectional data communication with the upper computer. The method comprises the steps that the printing device establishes communication connection with the data processing server, and sends data which is to be printed and is transmitted from the upper computer to the data processing server; the received data to be printed are converted into a bar-like code; the printing device receives the bar-like code data in preset time; and the bar-like code data and the corresponding data to be printed are sorted and printed. According to the invention, without modifying an upper layer application, an original checkout printer is replaced by the system which is provided by the invention and can be easily in butt joint with an Internet payment mode.