The invention discloses a heat pump clothes dryer which is used for being connected with a water tank. The heat pump clothes dryer comprises a cylinder body, a circulating air duct, a heat pump system, a circulating fan, a water collecting container, a water pump and a one-way valve, wherein an air inlet and an air outlet are arranged in the cylinder body; the circulating air duct is connected with the air inlet and the air outlet; at least one part of the heat pump system is arranged in the circulating air duct; at least one part of the circulating fan is arranged in the circulating duct; the water collecting container is used for collecting condensation water generated by the heat pump system and communicates with the water tank and the circulating air duct; the water tank communicates with the water collecting container through a water guide pipe; the water pump is connected to the water guide pipe; and the one-way valve only allows water of the water collecting container to flow to the water tank, is connected to the water guide pipe and is arranged between the water pump and the water tank. The heat pump clothes dryer according to the embodiments of the present invention has the advantage of high clothes drying efficiency.