The invention provides a whole process product quality online control system, which can achieve the on-line dynamic optimization of the product quality of procedures of the whole process, and thus improving the stability of the product quality. The system includes a specification making module, a process control system of each procedure, and a controller, the process control system includes a CPS-based dynamic product quality control module, the specification making module sets the quality indexes of the whole process and technological standards, the dynamic product quality control module acquires the product quality information of a previous procedure and the technological parameter setting value in the previous procedure, performs dynamic quality control and optimization of the obtained product quality information and the technological parameter setting value according to the set quality index and process specification of the whole process, and sends the optimized technological parameters to the controller, and the controller executes the optimized technological parameters. The whole process product quality online control system is applicable to the technical field of automatic control.