The invention discloses a novel large-volume medicine bottle. The novel large-volume medicine bottle comprises a bottle body and a bottle cap, wherein the bottle body and the bottle cap are connected in a threaded mode. A division bar structure is additionally arranged inside the bottle body, is inserted into the bottle body from top to bottom and is connected to the inner wall of the bottle body through a groove, the end of the division bar structure is flush with a bottle opening, the bottle opening is sealed by a sealing film, and the sealing film is connected to the end of the division bar structure and the bottle opening in a bonded mode and is divided into a plurality of independent tear-able sheet structures by the end of the division bar structure and the bottle opening. According to the novel large-volume medicine bottle, the structural design is reasonable, the functions are unique, medicine inside the bottle body can be effectively separated by the division bar structure arranged inside the bottle body, the tear-able sealing film is adopted, and therefore staged use of the medicine inside the bottle body can be realized, the probability that the medicine is affected with damp or oxidized can be effectively lowered, the quality of the medicine can be guaranteed, and the safety of using the medicine can be improved for people.