The invention discloses an isolated riding express carrying box. The isolated riding express carrying box mainly consists of a box body, a carrying box locking structure (1) mounted on the top surface of the box body, and carrying box opening/closing structures (2) distributed at four corners of the bottom of the box body. Compared with a traditional express carrying box, the isolated riding express carrying box has the following advantages: the isolated riding express carrying box has an opening/closing function, can synchronously open four box bodies for totally horizontal placement, or can singly open one side box wall to conveniently take goods, prominently improves the convenience of goods storage and taking by couriers, provides effective guarantee for goods safety through a locking function, and is higher in practicability.