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发明授权
CN106086182B PCYOX1蛋白在作为缺血性脑卒中生物标志物中的应用 有权

PCYOX1蛋白在作为缺血性脑卒中生物标志物中的应用
摘要：
本发明公开了PCYOX1蛋白在作为缺血性脑卒中生物标志物中的应用。具体公开了PCYOX1蛋白或其活性片段、或者检测PCYOX1蛋白或其活性片段的物质在诊断缺血性脑卒中和/或评估罹患缺血性脑卒中风险的产品中的应用。本发明公开了一种与脑卒中相关的蛋白PCYOX1，并进一步证实该PCYOX1蛋白或其活性片段在脑卒中组织中表达下调。利用该蛋白检测脑卒中不仅能够快速有效的做到早期检测，而且为基因治疗、药物治疗等临床应用提供了治疗靶点和重要依据。
摘要（英）：

The invention discloses an application of PCYOX1 (Prenylcysteine oxidase 1) protein as a biomarker of ischemic cerebral stroke, and particularly discloses the application of the PCYOX1 protein, an active fragment of the PCYOX1 protein or a substance for detecting the PCYOX1 protein or the active fragment of the PCYOX1 protein in a product for diagnosing ischemic cerebral stroke and/or evaluating the risk of suffering from ischemic cerebral stroke. The PCYOX1 protein related with cerebral stroke is provided, and down-regulated expression of the PCYOX1 protein or the active fragment of the PCYOX1 protein in the cerebral stroke tissue is further proved. With the adoption of the protein for detecting cerebral stroke, not only can early detection be realized rapidly and effectively, but also therapeutic targets and important basis are provided for clinical applications such as gene therapy, drug therapy and the like.

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