The invention relates to a leather-making auxiliary agent prepared from leather waste and amino silicon oil and a production method of the tanning auxiliary agent. According to the production method of the leather-making auxiliary agent, leather-making waste (comprising the leather-making waste containing chromium and the leather-making waste containing no chromium) is hydrolyzed and then reacts with the amino silicon oil, and then two leather-making auxiliary agents are prepared. The leather-making auxiliary agents have good filling performance, by the adoption of the leather-making auxiliary agents, leather is hardened, and the natural performance of the leather is kept; and the leather-making auxiliary agents can be combined with hide fiber, so that the tear strength of the leather is improved. By the adoption of the leather-making auxiliary agent prepared from the leather waste and the amino silicon oil and the production method of the leather-making auxiliary agent, the problems of accumulation of a large amount of leather solid waste and the pollution thereof to environment are relieved, resource utilization of the leather waste can be achieved, and the application prospect is quite broad.