The invention discloses a wide-area protection, control integration system and a method of forming an integration mode, and relates to the power system safe stable control technology field. The integration system is formed by connecting at least three substation area main station modules together, and the three substation area main station modules are respectively connected with a communication network, which is connected with a wide-area host module. The substation area main station modules are used to acquire total station electrical quantity information, and are used for information interaction with adjacent stations. The communication network is responsible for communication between substation area main stations, and is used to gather the electrical quantity information and the wide-area protection motion information of the substation area main stations, and is used to upload the above mentioned information to a wide-area host. The wide-area host module is used to realize a wide-area control function, and then a wide-area protection and control function integration mode is realized. The three defense lines of the power system are organically combined together in a multidirectional and multilayer way, and the relation among the three defense lines is coordinated, and therefore a foundation of realizing the wide-area protection and control integration system is laid.