The invention discloses a welding system for a lamp tube wire and a power board. The welding system comprises an angle adjustment device, a conveying device, a wire welding area and a power board welding area, wherein the conveying device is used for conveying a lamp tube, and the wire welding area and the power board welding area are arranged on the two sides of the conveying device correspondingly. After passing the angle adjustment device, the lamp tube enters the wire welding area and the power board welding area. The angle adjustment device adjusts the lamp tube so that a lamp strip can be located at the bottom of the lamp tube. The wire welding area is provided with a wire feeding mechanism, a first welding rod, a first spot welding driving assembly and a wire cutting assembly, wherein the wire feeding mechanism is used for pushing the wire to a wire spot welding position, the first welding rod is used for welding the wire to the lamp strip, the first spot welding driving assembly is used for driving the first welding rod to move, and the wire cutting assembly is used for cutting the wire. A power board positioning platform is arranged in the position, on one side of the power board welding area, of the conveying device and located at an opening of the lamp tube and moves along with the lamp tube. The power board welding area is provided with a second welding rod for welding the lamp strip and the power board together and a second spot welding driving assembly for driving the second welding rod to move. According to the welding system for the lamp tube wire and the power board, automatic welding of the lamp tube wire and the power board can be achieved.