The invention discloses a lane changing collision preventing control method with multiple modes and based on wire control steering, and aims to improve the safety when an automobile under all weathers and under all terrain working conditions changes a lane. In order to solve the problem that because of the limitation of the view field of a driver, the influence of bad weathers of fog, rain, snow and the like, and the influence of different road surface adhering conditions, the driver often cannot well control the driving situation of a rear automobile in a target lane, so that a collision accident is easy to occur, according to the relative motion state of a host automobile and the rear automobile in the rear of the target lane, and the difference of the danger degrees of lane changing, three kinds of lane changing collision preventing modes including an early warning lane changing collision preventing mode, an early warning and semi-automatic control lane changing collision preventing mode, and an early warning and full-automatic control lane changing collision preventing mode are set. The whole system comprises an information acquisition layer, a policy-making layer and an executing layer, wherein the information acquisition layer comprises a sensor module and an artificial selection module; the policy-making layer comprises a driver steering intention recognizing module and an auxiliary control module; and the executing layer comprises a wire control steering system and some human-machine interfaces.