The invention discloses a method for preparing 4-amino imine coumarin derivatives. The method for preparing 4-amino imine coumarin derivatives comprises the following steps: adding a cuprous catalyst, an additive and cyanophenol in a reaction vessel, wherein the additive is any one of triethylamine, tetramethylethylenediamine, 1,8- diazabicyclo undec-7-alkene, potassium carbonate or cesium carbonate; then adding an organic solvent; finally adding a terminal alkyne compound and p-toluenesulfonyl azide in the reaction container; carrying out heating reaction for 3-7 hours on a reaction mixture at the room temperature to the temperature of 110 DEG C; tracking with a thin-layer chromatography in a reaction process; after reaction is finished, filtering the mixture; washing a filter cake; after merging filtrate, concentrating the filtrate; and carrying out column chromatography isolation to obtain an amine compound as a final product. The 4-amino imine coumarin derivatives are prepared by a 'one-pot method', the reaction efficiency is improved greatly, aftertreatment is simple, and the industrial application prospect is good.