The invention relates to a large pipeline system provided with a telescopic and movable passage. The telescopic and movable passage comprises a moving device and fixed devices located at two ends of the moving device respectively, wherein the moving device comprises a sleeve and moving tube joints located at two ends of the sleeve respectively, one end of each moving pipe joint extends into the corresponding end of the sleeve and reciprocates in the sleeve under the action of a hydraulic telescopic mechanism, a sleeve flange is mounted at each of two ends of the sleeve, and a telescopic flange is mounted between the corresponding moving pipe joint and the sleeve; connecting rods penetrate the corresponding telescopic flanges and the sleeve flanges sequentially and are matched with nuts; the fixed devices comprise fixed pipe joints located at two ends of the moving device respectively, a fixed flange and a moving flange are arranged on each fixing pipe joint and the corresponding moving pipe joint respectively, and connecting bolts penetrate the corresponding fixed flanges and moving flanges sequentially and are matched with nuts. The system is good in seal property and convenient to dismount, and helps workers and equipment enter the pipeline system for working.