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发明授权
CN106153922B 一种结肠癌预后预测标志物及其检测方法 有权

一种结肠癌预后预测标志物及其检测方法
摘要：
本发明公开一种结肠癌预后预测标志物及其检测方法，其中，所述结肠癌预后预测标志物为PBRM1蛋白。本发明的PBRM1蛋白可以有效区分结肠癌病人术后生存期，从而为结肠癌预后诊断提供了新途径，为临床医生对于结肠癌病情分析提供了参考依据。本发明通过对样本组织进行免疫组织化学测定，当检测出样本组织的染色指数≥6时，判断为PBRM1蛋白高表达，提示结肠癌患者术后生存期长；反之，当检测出样本组织的染色指数
摘要（英）：

The invention discloses a colon cancer prognosis prediction marker and a detection method thereof. The colon cancer prognosis prediction marker is PBRM1 protein. According to the invention, the PBRM1 protein can effectively distinguish the postoperative lifetime of a colon cancer patient, thus a new way is provided for the colon cancer prognosis diagnosis, and a reference basis is provided for a clinical doctor to analyze the colon cancer state. According to the invention, the sample tissue is subjected to immunohistochemical determination; if the dyeing index of the sample tissue is greater than or equal to 6, high expression of PBRM1 protein is judged, which indicates long postoperative lifetime of the colon cancer patient; and if the dyeing index of the sample tissue is less than 6, low expression of PBRM1 protein is judged, which indicates short postoperative lifetime of the colon cancer patient.

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