The invention discloses an antibacterial simulation solid wooden cabinet. The antibacterial simulation solid wooden cabinet comprises a cabinet main body; a working device is mounted at the upper end of the cabinet main body; an antibacterial device is mounted at the upper end of the inner cavity of the cabinet main body; the antibacterial device is connected with the working device; a placement plate is mounted at the lower end of the inner cavity of the cabinet main body; a detecting device is arranged at each of the two ends of an inner wall of the cabinet main body; a ventilating device is mounted at each of the two ends of the cabinet main body, and one end of each ventilating device extends into the inner cavity of the cabinet main body; a bacteria isolating device is mounted in the inner cavity of each ventilating device; a control device is mounted in the inner cavity of the cabinet main body; an output end of the control device is electrically connected with the input end of each of the working device, the antibacterial device and the detecting devices. The antibacterial simulation solid wooden cabinet is easy to use and convenient to mount, facilitates the use of a user, and has very good convenience during a using process of the user.