利索-全球专利检索

  1. 登录
  2. 注册
发明公开
CN106176985A 暗绿紫堇有效部位及其制备方法和应用 无效 - 驳回

暗绿紫堇有效部位及其制备方法和应用
摘要：
暗绿紫堇有效部位及其制备方法和应用，属于植物提取物技术领域。选自暗绿紫堇乙酸乙酯部位、暗绿紫堇正丁醇部位、暗绿紫堇水相萃取部位中的一种或两种以上的任意质量比的混合物。将暗绿紫堇全草粉碎，加入体积百分比浓度65~95%乙醇溶液回流提取，将所得提取液浓缩、干燥，得浸膏；将浸膏加蒸馏水分散，得浸膏分散液，依次用石油醚、乙酸乙酯和正丁醇作为溶剂萃取浸膏分散液，挥去溶剂后得暗绿紫堇乙酸乙酯部位、暗绿紫堇正丁醇部位；将萃取后的浸膏分散液浓缩、干燥，得暗绿紫堇水相萃取部位。本发明的暗绿紫堇有效部位在制备抑制CDC25酶药物方面的应用，能够用于制备抗肿瘤药物。
摘要（英）：

The invention provides effective corydalis melanochlora extract and a preparation method and application thereof and belongs to the technical field of plant extract. The corydalis-melanochlora effective extract is characterized by being selected from a mixture of optional mass proportion of one or more than two kinds of corydalis melanochlora ethyl acetate extract, corydalis melanochlora n-butyl alcohol extract and corydalis melanochlora water-phase extract. The preparation method includes: smashing the corydalis melanochlora completely, adding an ethanol solution 65-95% in volume percent concentration for reflux extraction, and subjecting an extract solution to concentrating and drying to obtain extractum; adding distilled water to the extractum for dispersion to obtain an extractum dispersion solution, extracting the extractum dispersion solution by sequentially taking petroleum ether, ethyl acetate and n-butyl alcohol as solvent, and volatilizing the solvent to obtain the corydalis melanochlora ethyl acetate extract and the corydalis melanochlora n-butyl alcohol extract; subjecting the extracted extractum dispersion solution to concentrating and drying to obtain the corydalis melanochlora water-phase extract. The application of the effective corydalis melanochlora extract in the aspect of preparation of CDC25 enzyme inhibiting drugs can be used for preparing antitumor drugs.

0/0