The invention relates to an automatic layout adjustment device. The device comprises a suction frame, suction nozzles, a layout adjustment cylinder, a stepped shaft and a return cylinder, wherein the multiple suction nozzles are mounted on the lower side of the suction frame in a sliding fit manner; the layout adjustment cylinder is fixedly mounted on the right side of the suction frame; shaft holes with diameters progressively increased sequentially are formed in all suction nozzles from the second suction nozzle from left to right; the stepped shaft is mounted at an output end of the layout adjustment cylinder, the diameter of the stepped shaft is progressively reduced sequentially from right to left, and the stepped shaft extends into the shaft holes and presses against the right side wall of the first suction nozzle; the return cylinder is mounted on the left side of the suction frame; and an output end of the return cylinder is fixed on the left side wall of the first suction nozzle. The device has the advantages as follows: the distance among the suction nozzles can be adjusted automatically, multiple products can be captured at a time, and the packaging efficiency of the products can be improved.