The invention provides a self-cleaning method for a water purification module and a washing machine using the method. The self-cleaning method for the water purification module comprises the following steps of starting a self-cleaning program of the water purification module, feeding water into the washing machine to a set level position, successively and repeatedly performing a heating-rinsing program and a clean water replacement and rinsing program, and stopping the heating-rinsing program and the clean water replacement and rinsing program until the water purification module is detected to be thoroughly cleaned, wherein the heating-rinsing procedure comprises the steps of: heating washing water, performing film rinsing, performing standing and performing film gas washing. Through the adoption of the self-cleaning method for the water purification module disclosed by the invention, impurities, macromolecular particles and the like on the surface of a filtration system of the water purification module can be stripped in time, the water purification effect of the water purification module is guaranteed, the service life of the water purification module is effectively prolonged, and the experience of users is greatly improved.