The invention discloses a lead alloy anode plate for electrochemical metallurgy and a manufacturing method of the lead alloy anode plate, and belongs to the technical field of electrochemical metallurgy. Alloy liquid is injected into a water-cooling iron mold; demolding is carried out when the surface layer of the alloy liquid in the water-cooling iron mold is completely solidified, and a semi-solidified lead alloy ingot is obtained; and then a dual-roller rolling mill is used for carrying out multi-pass reduction on the semi-solidified lead alloy ingot, the total reduction is not lower than 70%, and the lead alloy anode plate with the thickness being 6-8 mm is obtained. The prepared lead alloy anode plate is of a crystal structure that the grain orientation is random, dimension is fine, and the quantity of special grain boundaries is large; the texture is fine and uniform, and the number of defects and gross segregation is remarkably reduced; and when the anode plate is applied to non-ferrous metal electrodeposition, the corrosion rate of the anode plate can be remarkably reduced, and the service life of the anode plate is prolonged to a great extent.