The invention provides a cable intermediate joint protection box, comprising a protection box body with a hollow interior. The protection box body comprises an upper protection box body and a lower protection box body with the same structure. Docking plates with through holes are arranged on the outer edges of the upper protection box body and the lower protection box body. An upper fixing half body is arranged at each of the left end and the right end of the upper protection box body. A lower fixing half body is arranged at each of the left end and the right end of the lower protection box body. Bended arc-shaped slots are arranged on the upper fixing half body and the lower fixing half body. The bended arc-shaped slots are connected with the interior of the protection box body. A limiting device is arranged at each of the two ends in the protection box body. In practical application, cables close to joint ends are distributed in the bended arc-shaped slots. When the cables are pulled, the axial pull borne by cable joints can be effectively reduced through adoption of the bended arc-shaped slots.