The invention discloses a hollow ball billet preparation device capable of reducing the manufacture cost of a titanium ball. The hollow ball billet preparation device comprises a forming device, a vibrating device, a locking device and a power transmission system, wherein the tail end of the power transmission system is connected with the vibrating device, the forming device is arranged on the vibrating device and provided with an opening and closing structure, and the side face of the forming device is matched with a working end of the locking device. By means of powder forming, the shortcomings of long route, more machining waste materials and high cost of a traditional machining process are overcome, the advantage of nearly net forming of powder metallurgy is taken, and the device for efficiently preparing the hollow titanium ball at low cost is developed. An eccentric wheel of the vibrating device rotates and drives the forming device to vertically vibrate, flowability of powder in feeding is improved, the defect of unfilled and non-compact billet core filling is overcome, the density of a billet core before pressing is increased, and a good assisting role is played for hollow titanium ball machining. The locking device performs locking by operating a lead screw through a handle, and the device is convenient in locking and simple to operate.