The invention discloses anti-wrinkle chlorophyll cream. The anti-wrinkle chlorophyll face cream is prepared from algae chlorophyll, antibacterial peptides, a ginseng extracting solution, a dendrobium huoshanense extract, an apple extracting solution, a peppermint extracting solution, a centella asiatica extract, a Chinese rose extracting solution, vegetable fat, a preservative, an emulsifier, supercritical propolis, royal jelly and deionized water. The invention further discloses a preparation method of the anti-wrinkle chlorophyll cream. The anti-wrinkle chlorophyll cream has the advantages that the cream has good permeability and is easy to absorb, and anti-wrinkle components effectively reach the deep-layer skin, repair skin wrinkles and suppress wrinkle regeneration renewable and delay skin aging.