The invention discloses a drum washing machine with a movable clothes loading and unloading opening. The drum washing machine comprises a shell, a bucket part, a rotatable drum, a door unit, a driving mechanism for driving the bucket part to rotate and a locking device, wherein the shell is provided with a front panel in which an opening is formed; the bucket part is provided with the clothes loading and unloading opening, and is arranged in the shell to move the clothes loading and unloading opening up and down in the opening; the rotatable drum is arranged in the bucket part; the door unit is arranged on the bucket part to open or close the clothes loading and unloading opening in a manner of moving up and down in the opening; the driving mechanism is arranged in the shell, and is connected with the bucket part; the locking device is structured to lock the bucket part and the door unit when the bucket part moves and separate the bucket part from the door unit when the bucket part is in a washing state. The drum washing machine with the movable clothes loading and unloading opening has the advantages of convenience for use, little wear to clothes, water source saving and the like, and the bucket part and the door unit can coaxially rotate to conveniently load and unload the clothes.