The invention belongs to the technical field of chemical analysis detection, and specifically relates to an analysis method for rapid combined determination of Ni, Cu, Fe, S, CaO, MgO, SiO2, Pb, Zn, As, Sb and Bi in flash smelting furnace slag. The method comprises: preparing a sample sheet, preparing a standard sample sheet, preparing an instrument drift correction sample sheet, determining the instrument drift correction sample sheet, selecting a special matrix correction method, determining the sample sheet, and calculating the analysis result. According to the present invention, the powder tableting is used, the sample pretreatment process is rapid, the rapid determining is achieved, the multi-element determination of one sample can be completed within 10 min, the labor efficiency is high, the operation is simple, the instrument analysis parameters and the matrix correction mode are unique, the appropriate instrument analysis parameters and the unique correction mode are explored, the technical problem that the partial element standard curve regression is not linear is solved, the multi-element combined determination can be performed, and the combined determination of the main component and the secondary components can be achieved.