The invention discloses a capsule preparation raw material drying and disinfecting mechanism which comprises a high-temperature high-pressure vapor generating device and a water bath drying mechanism. The output end of the high-temperature high-pressure vapor generating device is connected with a tank body through a steel pipe. A feed port is formed in the top of the tank body. A driving device is installed on the top of the tank body. An output shaft of the driving device is connected with one end of a transmission rod. The end, away from the driving device, of the transmission rod penetrates through the side wall of the tank body and extends into an inner cavity of the tank body. Stirring blades are installed on the side wall of the transmission rod. A discharge pipe is arranged at the bottom of the tank body. The discharge end of the discharge pipe is located over a feed pipe of the water bath drying mechanism. The water bath drying mechanism comprises the feed pipe, an inner container, a shell, a copper pipe, a discharge plate, a discharging pipe, an electric heating pipe and a water injection pipe. The capsule preparation raw material drying and disinfecting mechanism is high in disinfecting efficiency, high in drying efficiency, simple in structure and convenient to use.