The invention provides a computer numerical control (CNC) drilling machine tool system which comprises a mechanical arm, multiple rows of machine tools arranged on the periphery of the mechanical arm, a control cabinet, a feeding device and a conveying device, wherein the control cabinet is respectively in control connection with the mechanical arm, the machine tools and the feeding device; the conveying device is connected with the feeding device; the mechanical arm is arranged on a guide rail and can perform reciprocating motion along the guide rail; translation devices are arranged on the machine tool; a drilling device comprises a clamping device and a drilling mechanism and is arranged on each of the translation devices, a sliding groove is formed in a base of the drilling device, and the drilling mechanism of the drilling device is mounted on the sliding groove; the conveying direction of the conveying device is vertical to the moving direction of each of the translation devices. The whole process of the computer numerical control drilling machine tool system provided by the invention is operated and controlled by the control cabinet, so that the intelligence and the high efficiency are realized, and the problems of lower manual operation efficiency, higher cost, worse quality and the like are solved.