The invention relates to the technical field of microbial fermentation enzyme preparations, and in particular relates to a solid state fermentation method of adenylic deaminase. The solid state fermentation method comprises the following steps: (1) carrying out strain activation, namely, taking aspergillus spore suspension, and inoculating the aspergillus spore suspension into a culture medium for culture; (2) carrying out seed preparation, namely, inoculating spore suspension into a seed shake flask culture medium according to the inoculation quantity of 1-2.5 %, thus obtaining a seed bacterial solution; (3) carrying out culturing in a seed tank, namely, inoculating the seed bacterial solution into the seed tank according to the inoculation quantity of 0.1-0.5 %, thus obtaining a seed culture solution, wherein the rotation speed is 50-150 rpm, and the ventilation ratio is 1: (0.3-1):1.2; and (4) carrying out solid state fermentation production, namely, inoculating the seed culture solution into a solid state fermentation culture medium for culturing. With the adoption of the fermentation method, the solid state fermentation method has the advantages that the activity of the adenylic deaminase achieves 1500-2100 U/mL, the enzyme activity level is high, the problems that at present, the production level of deaminase is low, and the production cost is high, are solved, and the solid state fermentation method has the large-scale industrial application value.