The invention discloses an anti-isolation structure for dry-mixed mortar. The anti-isolation structure comprises a conveying assembly, a storage barrel, an anti-isolation assembly, a rotary drive assembly, supporting frames and a material car; the conveying assembly comprises a conveying bracket fixedly arranged on the ground; a conveying housing is fixedly connected on the conveying bracket; and a conveyor belt is arranged in the conveying housing. According to the anti-isolation structure disclosed by the invention, a plurality of groups of vertical isolation channels are arranged on the anti-isolation assembly, and each group of vertical isolation channels separately communicates with a plurality of transverse isolation channels and is matched with action of the anti-isolation bracket, so that mortar can be prevented from being isolated very well, and mortar quality during building can be improved. The anti-isolation structure disclosed by the invention is suitable for being widely applied in the technical field of dry-mixed mortar equipment.