The invention discloses a flue-cured tobacco cultivation method capable of effectively controlling high-nitrogen soil fertility. The cultivation method comprises the following steps: A. before transplantation, making a pond in a tobacco field, and applying a phosphate fertilizer in the pond; B. during the transplantation, applying an organic magnesium potassium sulfate fertilizer, an organic induced disease-resistant agent, a microbial inoculant and biochar into the pond, and after finishing the transplantation, applying well-rotted farmyard manure and covering the pond; C. 10-15 days after the transplantation, applying an all-water-soluble organic fertilizer solution in the pond; D. 40-60 days after the transplantation, spraying an organic potassium fertilizer and a boron zinc molybdenum fertilizer; and E. 55-60 days after the transplantation, carrying out tip pruning on the tobacco plants. The method is simple to operate, and is capable of effectively controlling the high-nitrogen soil fertility and lowering the residual nitrogen element in the high-nitrogen soil. The first batch of nitrogen element which can be easily decomposed in the soil is firstly released, thereby satisfying the demands of early growth and quick tillering of the transplanted tobacco plants. Meanwhile, the method can effectively control the phenomena of regreening and excessive vegetative growth in the tobacco plants.