The invention discloses a local slimming injection for dissolving fat. The local slimming injection is characterized in that 2-9ml of a sodium bicarbonate injection with a mass percentage of 5% and 1-8 micrograms of epinephrine are added into 1-9ml of a lidocaine injection with a mass percentage of 1% for local injection; 0.1-0.2ml of L-carnitine is dissolved in 5-10ml of a phosphatidylcholine injection for carrying out local injection on fat of a body; injection parts comprise face, abdomen, legs and the like. After a fat dissolving injection is injected into a fat layer of the body, expansion and decomposition of a stubborn fat layer can be effectively accelerated, so that the fat is more easily decomposed into fatty acid for replacing the fat to supply the energy to the body; after the fat is dissolved by injecting the local sliming injection, the fat does not rebound; through the adoption of a non-invasive therapy method, the damage to the body is avoided; surgery operation and fat suction are avoided; the pain of paints caused by a fat suction operation is avoided; the occurrence of the situations that skin is uneven and complications are caused can be avoided; the local sliming injection is free of dieting, free of operation, quick in effect and lasting in therapeutic effect, and is capable of eliminating stubborn proud flesh and improving skin texture.