The invention provides an amino-acid ester bromide type chiral ionic liquid and a preparation method thereof. The structural formual of the amino-acid ester bromide type chiral ionic liquid is as shown in the specification. In the structural formula, R is a variable group of alpha-amino acid; and R' is an alkyl group with the number of carbon atoms being 1-3. Chirality of the amino-acid ester bromide type chiral ionic liquid is positioned on amino acid cation. Amino group is connected to a bulk group. Then, stereoselectivity is stronger, and the product has structural diversity and designability. The amino-acid ester bromide type chiral ionic liquid of the invention has characteristics of an ionic liquid, such as non-volatile property, nontoxicity, no pollution, wide liquid range, low vapor pressure, good conductivity, strong polarity and the like, and also has characteristics of a chiral substance, such as high selectivity, chiral induction effect and the like. The product can be used in chiral catalysis and chiral separation, and is very suitable for large-scale production in the industry of fine chemical engineering. A preparation method of the amino-acid ester bromide type chiral ionic liquid has advantages of rich sources of raw materials, low cost and simple operation.