The embodiment of the invention discloses a control system used for an autonomous mobile robot platform. The control system comprises a robot platform and a server. The server comprises a human-computer interaction module, a data processing module and a route planning module. The embodiment of the invention also discloses a control method and device used for the autonomous mobile robot platform. With application of the control system used for the autonomous mobile robot platform and the control method and device thereof, omnidirectional movement of the robot platform can be realized by using a structure of multiple synchronous wheels so as to have flexible and high-precision plane movement capacity; and a speedometer is corrected by laser radar and an inertial navigation system by using an extended Kalman filtering algorithm, two sets of corrected positions are weighted and fused to act as spatial locating of the robot platform, and error caused by long time of operation of the robot platform is corrected by the contour characteristics of the environment so that the locating precision and the movement precision of the robot platform in long time of movement can be guaranteed, and multiple robot platforms can simultaneously operate according to the requirements to cooperatively complete the task.