The invention designs an intelligent substation secondary equipment safety measure bill automatic construction method and device. An associated device and a secondary loop link are obtained, an associated equipment information database is established, and the scope of influence is determined. The secondary equipment software pressing plate information and hard pressing plate information with the need of withdrawal in maintainance is obtained. According to the obtained secondary equipment software pressing plate information and hard pressing plate information, with the combination of safety measures, a bill is made. The accuracy of secondary equipment safety measures is improved, the safety measures are executed strictly according to a sequence, the false lock of equipment is prevented, and the operation is simple.