Provided is a safety cabinet. The safety cabinet comprises an enclosure, doors which can move in an open position and a close position, and interlock mechanisms. Each interlock mechanism comprises an installation element, a fusible connection rod, a catch and a bias mechanism, wherein the fusible connection rod connects the installation element and the catch; and the catch is capable of moving between a contraction position and an interlock position. A non interlock relation is formed between the catches, the doors, and the housing in the contraction position. An interlock relation is formed between the catches, the doors and the enclosure when the doors are in the closed position in the interlock position. The bias mechanisms are configured to push the catches to the interlock position. The catches are constrained to can't move to the interlock position by the fusible connection rods. The fusible connection rods are configured to be fused at a preset temperature so as to allow the installation elements to be disconnected with the installation elements, thereby permitting the bias mechanisms to move the catches to the interlock position relative to the installation elements.