The invention relates to a method for simultaneous adsorption separation of multiple raw materials by using a liquid phase simulation moving bed. According to the method, a liquid phase simulation moving bed containing n bed layers is divided into m adsorption separation sections, the bed layer between the two adjacent desorbent D injection points is adopted as the one adsorption separation section, various adsorption separation sections are sequentially arranged along an inside-bed-layer fluid flowing direction, the bed layer between the injected stream and the taken stream connected to the injected stream form the function area of the simulation moving bed, and each adsorption separation section comprises a desorption zone, a purification zone, an adsorption zone and an isolation zone. According to the present invention, with the method, a variety of the adsorption of raw materials having different compositions are respectively injected into different adsorption separation sections to simultaneously separate so as to obtain one or more than one high-purity components, such that the treatment capacity of the existing simulation moving bed can be completely utilized.