The invention provides a sealed and safe bromination reaction device, which comprises a reactor, a conical feeding hopper, a stirrer, a constant pressure feeding device and a sampling device, wherein a butterfly valve is arranged at a connecting part of the conical feeding hopper and the reactor; vibrators are arranged at the outer side of the conical feeding hopper; a hopper cover is arranged at the top of the conical feeding hopper; the constant pressure feeding device comprises a constant pressure feeding device body and a constant pressure pipeline; the top of the constant pressure feeding device body is provided with an alkaline liquor tank; the sampling device is connected with a vacuum pump. Compared with the prior art, the sealed and safe bromination reaction device has the advantages that through the arrangement of the conical feeding hopper and the butterfly valve, the solid feeding is more convenient; the blockage and the dust flying cannot easily occur; the constant pressure feeding device is installed, so that the bromine dripping is smoother; the alkaline liquor tank is installed for adsorbing unreacted bromine steam; the sampling device is installed for avoiding the contact with poisonous bromine steam; the device structure is simple; the design is reasonable; the operation is convenient; the sealing performance and the safety are high; the application range is wide; application prospects are wide.